Artificial pancreas systems for managing type 1 diabetes have progressed from research into clinical practice, revealing important considerations for future advancements. To mimic the healthy pancreas, basal exogenous insulin administration replicates the background insulin produced by the pancreas and additional insulin boluses are required at mealtimes, when glucose concentrations rise in response to carbohydrate consumption. As the burden of diabetes self-management remains high, there is a growing need for devices that continuously monitor glucose concentrations and automatically adjust insulin delivery rates – the so-called ‘artificial pancreas’ – to help maintain blood glucose in a healthy range. The presentation shows advances in artificial pancreas systems and considerations for continued progress toward widespread clinical adoption.